Multiple Chemical Sensitivity Etiology

Airway Genetics and Ambient Combustion Aerosol

Assigning blame to everything but the largest exposure of all - the PM2.5, UFPM, and PM LPS (Gillespie 2013, Pedata 2010, Araujo 2009, Phalen 2009, Schmid 2009, Valavanidis 2008, Calderon-Garciduenas 2008, deHaar 2006, Kreyling 2006, 2004, Donaldson 2003, Oberdorster 1996) particulate vector driven load of chemicals and heavy metals attached to carbonaceous cores (Bonvallot 2001, 2000, Boland 2000, 1999, Baeza-Squiban 1999, Bayram 1998, Kumagai 1997, Thomas 1997) -

present in every breath 24/7/365 - persistent, prolonged, and cumulative residence time  (Gerde 2001 Fung 1999 Yeh 1996 Gerde 1991(Nyberg 1989, Burtscher 1986, Thompson 1989, Molliere 1987, Burtscher 1986,Harmsen 1985, Lundborg 1984, Adamson 1982, Natusch 1978) -

relentless horizontal coning of chimney and tailpipe emissions - gasoline and diesel exhaust - in defiance of 15 years conclusive and precise evidence since publication of the 1999 Criteria - rum dumb action of PM aerosol components on the critical MCS sensory receptors - including expression of TRPA1, TRPV1, and substance P (Deering-Rice 2011, Hazari 2011, Costa 2010, Taylor-Clark 2010, Caceres 2009, Anand 2008Bessac 2008), Nassenstein 2008Bautista 2006Inoue 2005, Kobayashi 2005, Veronesi 2001),

breakdown of airway epithelium (Calderon-Garciduenas 2008, 2003, 2001, 2000, Veronesi 2001, Meggs 1997),

involvement of PM with lung macrophages (Hiraiwa 2014, 2013, Hogg 2009, Goto 2004, Mukae 2001), liver kupffer cells Calderon-Garciduenas 2008, and brain microglia Block 2012, 2009, Calderon-Garciduenas 2008),

activation of bone marrow leukocyte release - especially premature granulocytes (band cells) and monocytes, increased liver production of acute phase proteins (Hiraiwa 2014, 2013, Hogg 2009, Goto 2004, Mukae 2001),

suppression of detox enzymes (Deluca 2010, Liptrott 2009, Oslund 2008, Chun 2002, Sterner-Kock 1999, Tinel 1999, Tanabe 1996, Tapner 1996, Nadin 1995, Stadler 1994, Khatsenko 1993),

penetration of UFPM to the CNS (Calderon-Garciduenas 2010Genter 2009, Matsui 2009, Elder 2006Lewis 2005) - and also applicable to ME/CFS (Maes 2012) - the 1999 Criteria are okay - the 2015 Criteria maintains them - but the 1999 language expressing and implying a low level of exposure in a non-inciting background atmosphere is false.

The technology and fuels behind 100 billion plus in health costs per year in the US (Pervin 2008, USDOTFHA 2000) will not be corrected if the problem is unacknowledged.

If non-professional you can Consensus author by passing the CAR Test.

The 2015 MCS Criteria Consensus article is MCS 3a.

The 90 page CAR Test with complete instructions is MCS 3aa both linked below.

Google: MCS Etiology

MCS 3a Criteria Amendment Research (CAR)

MCS 3a AKA Multiple Chemical Sensitivity:  2015 Consensus Criteria

MCS 3aa Etiology: Consensus Author CAR Test (SPC)

MCS 3b CAR References

Though not necessary - all information is presented free on the website - the above and additional information is also available in convenient 100 page books - sold at cost - no markup - by contacting azmtmike@yahoo.com. Two volumes containing Criteria and CAR Test are 10.00 each (20.00 for both) - the third volume - Personal, Home, Community Management completes the 3 volume set for 25.00. All prices include shipping.

Check or money order (please also notify me by E-mail if you have sent payment - azmtmike@yahoo.com) payable to:

Michael E. Badolato Jr

90 W. Madison Ave'

Suite E-217

Belgrade, MT 59714

Best wishes,

Mike

Views: 62

Reply to This

© 2024   Created by michael edward badolato jr.   Powered by

Badges  |  Report an Issue  |  Terms of Service