Multiple Chemical Sensitivity Etiology
Airway Genetics and Ambient Combustion Aerosol
Impossibly Good
A slower paced, reduced consumption, non combustion lifestyle is needed or human beings will go extinct due to loss of environment and resources.
Mgt 101 Consume Less or Extinction
Mgt 101a Impossibly Good City Design
9 Point Summary:
1) Man began cooking and heating with fire. Inhaling smoke predisposed for infections limiting life expectancy (Boman 2006).
2) Man developed antibiotics preventing fatality from infections greatly increasing life expectancy despite the inhalation of smoke and liquid fuel combustion byproducts (Yoshikawa 2000).
3) Smoke and liquid fuel combustion byproducts - combined with individual genetic vulnerability - plague the second half of life with degenerative disease due to penetration of particle agglomerates with adsorbed hydrocarbons and singlet non-agglomerated nanoparticles
Deering-Rice 2011, Hazari 2011, Li 2011, Taylor-Clark 2010, Baulig 2009, 2003a, Calderon-Garciduenas 2008, 2000, Veronesi 2003, 2002a, 2002b, 2001, 2000, 1999a, 1999b, Agopyan 2003, Bonvallot 2001, 2000, Gerde 2001, 1997, Oortgiesen 2000, Roy 2000, Miyabara 1998,1998a, Steerenberg 1998, Meggs 1997
OSHA 2012, Block 2009, Pakkanen 2003, Schauer 2002, 2001, 1999, US DOT FHA 2000, Society of Automotive Engineers SAE 940233 1994
Lucchini 2012, Mohankumar 2008, Inoue 2005, Kittelson 1998, Cadle 1999, Kleeman 1999
Fine particles expected to reach the CNS via trigeminal and olfactory nerve pathways
MCS 11, Calderon-Garciduenas 2010, Genter 2009, Matsui 2009, Elder 2006, Lewis 2005
4) Diseases due to smoke - wood and tobacco - and liquid fuel combustion byproducts - diesel, gasoline, propane, white gas - include Multiple Chemical Sensitivity (Deering-Rice 2011, Kunkler 2011,Taylor-Clark 2010, Bessac 2008, Nassenstein 2008, Nilius 2007), Alzheimers (Calderon-Garciduenas 2008), Parkinsons (Block 2009, 2004, Calderon-Garciduenas 2008, Veronesi 2005), cancer (Krivoshto 2008), chronic obstructive pulmonary disease (Li 2011), and exascerbation of heart disease (Hazari 2011).
5) Exposure of mother and developing fetus to the continuous combustion byproduct aerosol has increased autism in newborn children.
"...Exposure to traffic-related air pollution, nitrogen dioxide, PM 2.5 and PM 10 during pregnancy and the first year of life was associated with autism..."
"...Measured and estimated exposures from ambient pollutant monitors and LUR model suggest associations between autism and prenatal air pollution exposure, mostly related to traffic sources...
...12-15% relative increase in odds of autism for 03 (ozone)...per 11.54 ppb increase and PM 2.5 per 4.68 ug/m3 increase..."
"...Living near a freeway was associated with autism...
...Autism is a developmental disorder characterized by significant deficits in social interaction and communication, accompanied by repetitive behaviors (American Psychiatric Association 2000)...
...autism has been associated...with diesel PM exposure in early childhood (Windham 2006)...
...Recent work examining the effects of benzo[a]pyrene, a common PAH, indicates that prenatal oral exposure in mice results in decreased neuronal plasticity and behavioral deficits (Brown 2007)..."
6) Abundant energy from combustion sources has resulted in unrestrained proliferation - population growth and consumption - and near complete loss of morality. Knowledge on this subject has been applied to developing drugs and futile emission control strategies - rather than changing the lifestyle.
7) Though often hard working with great achievement - there is conformity to an immoral lifestyle - drive instead of walk, thermostats set high, junk food instead of wholesome, violent entertainment, mostly oblivious of the environment - and a willingness to take drugs as a solution.
8) That people would recognize morally deficient social values and change behavior seems impossible. Required is a moral and intellectual exertion - a self scrutiny of one's own attitude, character, behavior, and motives - and a rejection of wasteful activities and products.
9) Good God, spirits of the universe, or whatever you believe - we have to be Impossibly Good.
Mgt 101 Consume Less or Extinction
Mgt 101a Impossibly Good City Design
Love 201 20 Commandments: Who's Overdoing It?
Multiple Chemical Sensitivity Etiology
Airway Genetics and Ambient Combustion Aerosol
Correct etiology applied to the majority of cases.
Sheds light on pollution caused disease in general - including MCS, Alzheimers, Parkinsons, cancer, COPD, and exascerbation of heart disease.
Recognizes there is no safe level of smoke and vehicle exhaust.
To quickly locate use search words MCS Etiology.
References
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American Psychiatric Association. Diagnosis and Statistical Manual of Mental Disorders 4th ed. Text Revision. Washington, DC 2000
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MCS 9 Airway Origins: PM and a Defective Scrubber.
MCS 10 Credible Proof: The Study of all Studies.
MCS 11 PM: Trigeminal and Olfactory Pathways.
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